Liposomes for Drug Delivery

Liposomes for Drug Delivery

Bergstrand, N. 2003. Liposomes for Drug Delivery: from Physico-chemical Studies to Applications. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertation form the Faculty of Science and Technology 826. 71pp. Uppsala.

Surfactants in Liposomes for Targeted Drug Delivery

Liposome is colloidal, vesicular structures capable of targeting to specific sites. Evans blue dye (hydrophilic dye) were formulated in liposomes using phosphatidyl choline, cholesterol and those liposomes were modified using surfactants surfactants span 20 , span 40 , span 80 or tween 80 at various molar ratio and optimized for its stable vesicular formation. The particle size and FTIR analysi...

Liposomes in topical drug delivery.

The possible use of liposomes as topical drug delivery vehicles for both water- and lipid-soluble drugs has been investigated. Data for two characteristic drugs, penicillin G and indoxole, are presented. Liposome uptake by the cornea is greatest for positively charged liposomes, less for negatively charged liposomes, and least for neutral liposomes, suggesting that the initial interaction betwe...

Heparosan-coated liposomes for drug delivery.

Liposomal encapsulation is a useful drug delivery strategy for small molecules, especially chemotherapeutic agents such as doxorubicin. Doxil® is a doxorubicin-containing liposome ("dox-liposome") that passively targets drug to tumors while reducing side effects caused by free drug permeating and poisoning healthy tissues. Polyethylene glycol (PEG) is the hydrophilic coating of Doxil® that prot...

Liposomes as Potential Drug Carrier Systems for Drug Delivery